Ammonium Acetate → HCID 14093519、化合物

HRID 1165291ノート

反応式

HRID 1165291 の反応式
[Cl-].[F:2][C:3]1[CH:17]=[CH:16][C:6]([C:7](=O)[CH2:8][N+]2C=CC=CC=2)=[CH:5][CH:4]=1.[F:18][C:19]1[CH:24]=[CH:23][C:22]([C:25](=O)[CH:26]=[CH:27][C:28]2[CH:33]=[CH:32][C:31]([N:34]([CH3:36])[CH3:35])=[CH:30][CH:29]=2)=[CH:21][CH:20]=1.C([O-])(=O)C.[NH4+:42]>C(O)(=O)C>[CH3:35][N:34]([CH3:36])[C:31]1[CH:32]=[CH:33][C:28]([C:27]2[CH:26]=[C:25]([C:22]3[CH:23]=[CH:24][C:19]([F:18])=[CH:20][CH:21]=3)[N:42]=[C:7]([C:6]3[CH:5]=[CH:4][C:3]([F:2])=[CH:17][CH:16]=3)[CH:8]=2)=[CH:29][CH:30]=1

参加物

5

反応物 3

HCID 517165Ammonium AcetateHCID 27792234-(Dimethylamino)-4'-fluorochalconeHCID 11021356HCID 11021356、化合物

生成物 1

HCID 14093519HCID 14093519、化合物

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒

実験手順

10.06 parts of 1-(4'-fluorophenacyl)-pyridinium chloride and 10.76 parts of 1-(4-fluorophenyl)-3-(4'-dimethylaminophenyl)-1-oxoprop-2-ene are heated at 130° C. for 81/2 hours together with 34 parts of ammonium acetate in 50 parts of glacial acetic acid. The mixture is stirred for 17 hours at room temperature, after which the precipitated colorless crystals are filtered off under suction, washed with methanol and water and dried at 60° C. in a drying oven to give 10.5 parts of 4-(4-dimethylamino-phenyl)-2,6-bis-(4'-fluorophenyl)-pyridine, which dissolves in glacial acetic acid to give an orange yellow coloration (λmax: 431 nm).

後処理

  1. filtrationafter which the precipitated colorless crystals are filtered off under suction
  2. washwashed with methanol and water
  3. customdried at 60° C. in a drying oven

出典と根拠

ORDレコード
ord-a62bfe1ceecd41729a32e21491b21f91
出典データセット
uspto-grants-1990_03
特許番号
US04908447

反応ノート

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