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Sulfuric Acid → Ammonia
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sulfuric Acid | HCID 1118 | — |
| 反応物 | 2-Naphthol | HCID 8663 | — |
| 反応物 | 1-Naphthalenesulfonic acid, 2-hydroxy- | HCID 11278 | — |
| 反応物 | 2-Naphthalenesulfonic acid, 6-(acetylamino)- | HCID 109713 | — |
| 生成物 | Ammonia | HCID 222 | — |
| 生成物 | 6-Amino-2-naphthalenesulfonic acid | HCID 7116 | — |
| 生成物 | Ammonium Bisulfite | HCID 10441651 | — |
反応手順
A single-vessel process for preparing 2-acetaminonaphthalene-6-sulfonic acid of high purity by sulfonating 2-hydroxynaphthalene with concentrated sulfuric acid, converting the 2-hydroxynaphthalenesulfonic acid formed with ammonia in the presence of ammonium hydrogensulfite into 2-amino-naphthalene-6-sulfonic acid (Bucherer reaction) and N-acetylating the latter to give 2-acetaminonaphthalene-6-sulfonic acid, which comprises, after diluting the sulfonating melt with water, substantially removing any impurities still present in the resulting aqueous solution of 2-hydroxynaphthalene-6-sulfonic acid, in particular 2-hydroxynaphthalene, by extraction with toluene or xylene and/or clarification using active carbon.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04908478 |
| 出典データセット | uspto-grants-1990_03 |
| ORD ID | ord-34ece30b6f094db299093682da7e5fa4 |
| 出典メモ | uspto-grants-1990_03 |