化工社化工社 化学情報印刷レポート · 研究参考用
Potassium Hydroxide → 4-chloro-2-(4-chlorophenyl)-5-{(6-chloro-3-pyridyl)-methyloxy}-3(2H)-pyridazinone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Potassium Hydroxide | HCID 14797 | — |
| 反応物 | (6-Chloropyridin-3-yl)methanol | HCID 177161 | — |
| 反応物 | 4,5-Dichloro-2-(4-chlorophenyl)-3(2H)-pyridazinone | HCID 779402 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 4-chloro-2-(4-chlorophenyl)-5-{(6-chloro-3-pyridyl)-methyloxy}-3(2H)-pyridazinone | HCID 3639225 | 61.2% |
反応手順
The procedures in Synthesis Example 2 were repeated by using 2.0 g (7.2 m mol) of 2-(4-chlorophenyl)-4,5-dichloro-3(2H)-pyridazinone, 1.1 g (7.7 m mol) of 6-chloro-3-pyridine methanol, 0.4 g of potassium hydroxide and 80 ml of N,N-dimethylformamide to give 1.7 g of the intended product (recrystallized from benzene/n-hexane).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04910201 |
| 出典データセット | uspto-grants-1990_03 |
| ORD ID | ord-6690ea97cf5545289c0658e98f2f1891 |
| 出典メモ | uspto-grants-1990_03 |