Chlorine → HCID 12445115、化合物
反応式
[Cl:1]Cl.[CH3:3][C:4]1[CH:8]([CH3:9])[C:7](=[O:10])[NH:6][N:5]=1>ClCCCl>[CH3:3][C:4]1[C:8]([CH3:9])([Cl:1])[C:7](=[O:10])[NH:6][N:5]=1参加物
4
実験手順
A chlorine gas was introduced into a solution of 3,4-dimethyl-2-pyrazolin-5-one in 1,2-dichloroethane, followed by gradual refluxing. After the reaction, the reaction mixture was cooled and filtered. The solvent was then distilled off. The residue in the form of an oil was recrystallized from a 1:1 mixture of benzene and petroleum ether, whereby 3,4-dimethyl-4-chloro-2-pyrazolin-5-one was obtained.
後処理
- customAfter the reaction
- temperaturethe reaction mixture was cooled
- filtrationfiltered
- distillationThe solvent was then distilled off
- customThe residue in the form of an oil was recrystallized from a 1:1 mixture of benzene and petroleum ether
出典と根拠
- ORDレコード
- ord-fadd21cfd8c446338dcf4771ccea57cf
- 出典データセット
- uspto-grants-2003_09
- 特許番号
- US06613456B2
反応ノート
読み込み中…