Ethyl Acetate → HCID 22993710、化合物

HRID 1167643ノート

反応式

HRID 1167643 の反応式
[O:1]1[CH:5]=[C:4]([C:6]([O:8][CH3:9])=[O:7])[C:3]([C:10]([O:12][CH3:13])=[O:11])=[CH:2]1.C(OCC)(=O)C.[H][H]>CO.[Rh]>[O:1]1[CH2:5][CH:4]([C:6]([O:8][CH3:9])=[O:7])[CH:3]([C:10]([O:12][CH3:13])=[O:11])[CH2:2]1

参加物

6

反応物 3

HCID 8857Ethyl AcetateHCID 303461Dimethyl furan-3,4-dicarboxylateHCID 178418361HCID 178418361、化合物

生成物 1

HCID 22993710HCID 22993710、化合物収率 100%

試薬・触媒・溶媒 2

HCID 23948Rhodium触媒HCID 887Methanol溶媒

実験手順

Dimethyl 3,4-furandicarboxylate (5.20 g, 28.0 mmol) was combined with 5% Rhodium/C in methanol (30 mL) and ethyl acetate (10 mL) in a Parr shaker bottle. The reaction was charged to 50 psi hydrogen and was shaken for 8.5 h. The reaction was filtered over celite, concentrated in vacuo to give the dimethyl 3,4-tetrahydrofuran dicarboxylate (5.2 g, 100%) as an oil MS (M−CH3OH)+=156.

後処理

  1. filtrationThe reaction was filtered over celite
  2. concentrationconcentrated in vacuo

出典と根拠

ORDレコード
ord-aadcb005d49e4a66a8b059231910b2b0
出典データセット
uspto-grants-2003_09
特許番号
US06620823B2

反応ノート

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