4-Aminomethyl-1-N-butylpiperidine → 5-Amino-N-[(1-butyl-4-piperidinyl)methyl]-6-chloro-2-propylimidazo[1,2-a]pyridine-8-carboxamide
反応式
[NH2:1][C:2]1[N:7]2[CH:8]=[C:9]([CH2:11][CH2:12][CH3:13])[N:10]=[C:6]2[C:5]([C:14]([OH:16])=O)=[CH:4][C:3]=1[Cl:17].[CH2:18]([N:22]1[CH2:27][CH2:26][CH:25]([CH2:28][NH2:29])[CH2:24][CH2:23]1)[CH2:19][CH2:20][CH3:21]>>[NH2:1][C:2]1[N:7]2[CH:8]=[C:9]([CH2:11][CH2:12][CH3:13])[N:10]=[C:6]2[C:5]([C:14]([NH:29][CH2:28][CH:25]2[CH2:26][CH2:27][N:22]([CH2:18][CH2:19][CH2:20][CH3:21])[CH2:23][CH2:24]2)=[O:16])=[CH:4][C:3]=1[Cl:17]参加物
3
実験手順
The title compound was prepared according to the procedure described in the step 3 in EXAMPLE 5 using 5-amino-6-chloro-2-propylimidazo[1,2-a]pyridine-8-carboxylic acid (EXAMPLE 16, Step 2) and 1-(1-butyl-4-piperidinyl)methanamine (EXAMPLE 1, METHOD A, Step 5).
出典と根拠
- ORDレコード
- ord-af39b832ae164c51afe93435ce9b4077
- 出典データセット
- uspto-grants-2003_09