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3-Hydroxy-2-hydroxymethyl-6-methylpyridine → 3-Hydroxy-6-methylpyridine-2-carbaldehyde
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Hydroxy-2-hydroxymethyl-6-methylpyridine | HCID 135128 | — |
| 触媒 | HCID 178418406 | HCID 178418406 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 3-Hydroxy-6-methylpyridine-2-carbaldehyde | HCID 12421986 | 7.1% |
反応手順
To a solution of 2-hydroxymethyl-6-methyl-pyridin-3-ol (1.0 g, 7.19 mmol) in methylene chloride (30 mL) at ambient temperature was added manganese dioxide (12.5 g, 143 mmol). The reactions was stirred for 48 hours, then filtered through celite and concentrated to give the title compound (0.070 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07098212B2 |
| 出典データセット | uspto-grants-2006_08 |
| ORD ID | ord-02ad876e63fb458292e9317dfd5c8fb7 |
| 出典メモ | uspto-grants-2006_08 |