Sodium Iodide → Iodopropyldimethylvinylsilane

HRID 1170069

反応式

HRID 1170069 の反応式
Cl[CH2:2][CH2:3][CH2:4][SiH2:5][CH:6]=[C:7]([CH3:9])[CH3:8].[I-:10].[Na+]>CC(CC)=O>[I:10][CH2:2][CH2:3][CH2:4][SiH2:5][CH:6]=[C:7]([CH3:9])[CH3:8]

参加物

4

反応物 2

HCID 5238Sodium IodideHCID 131715857Chloropropyldimethylvinylsilane

生成物 1

HCID 131728415Iodopropyldimethylvinylsilane収率 53.6%

試薬・触媒・溶媒 1

HCID 6569Methyl Ethyl Ketone溶媒

反応条件

温度
75 °C

実験手順

To a stirring solution of chloropropyldimethylvinylsilane (645 g) in ethyl methyl ketone (4.65 L), sodium iodide (1.215 Kg) was added under nitrogen and the mixture heated at 75° C. for 24 hr. The reaction mixture was cooled and added D.M. Water (1.62 L) and separated organic layer. The aqueous layer was re-extracted with ethyl methyl ketone (1.16 L) and the extract combined with the organic layer. The organic layer was dried on sodium sulfate and evaporated to dryness. Orange oil was purified by vacuum distillation to give colourless liquid the title product (540 g).

後処理

  1. temperatureThe reaction mixture was cooled
  2. additionadded D.M
  3. customWater (1.62 L) and separated organic layer
  4. extractionThe aqueous layer was re-extracted with ethyl methyl ketone (1.16 L)
  5. customThe organic layer was dried on sodium sulfate
  6. customevaporated to dryness
  7. distillationOrange oil was purified by vacuum distillation

出典と根拠

ORDレコード
ord-8205c8f0b2644da4b9373ef46ef7c4f7
出典データセット
uspto-grants-2010_11
特許番号
US07825257B1

関連ノート

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