4-[3-(4-Benzyloxy-phenyl)-1-methyl-1H-pyrazol-4-yl]-pyridine → 4-[1-Methyl-3-(4-triisopropylsilanyloxymethyl-phenyl)-1H-pyrazol-4-yl]-pyridine

HRID 1170351ノート

反応式

HRID 1170351 の反応式
C(O[C:9]1[CH:14]=[CH:13][C:12]([C:15]2[C:19]([C:20]3[CH:25]=[CH:24][N:23]=[CH:22][CH:21]=3)=[CH:18][N:17]([CH3:26])[N:16]=2)=[CH:11][CH:10]=1)C1C=CC=CC=1.N1C=CC(CC(C2C=CC([CH2:42][O:43][Si:44]([CH:51]([CH3:53])[CH3:52])([CH:48]([CH3:50])[CH3:49])[CH:45]([CH3:47])[CH3:46])=CC=2)=O)=CC=1>>[CH3:26][N:17]1[CH:18]=[C:19]([C:20]2[CH:21]=[CH:22][N:23]=[CH:24][CH:25]=2)[C:15]([C:12]2[CH:11]=[CH:10][C:9]([CH2:42][O:43][Si:44]([CH:45]([CH3:47])[CH3:46])([CH:51]([CH3:53])[CH3:52])[CH:48]([CH3:50])[CH3:49])=[CH:14][CH:13]=2)=[N:16]1

参加物

3

反応物 2

HCID 442349314-[3-(4-Benzyloxy-phenyl)-1-methyl-1H-pyrazol-4-yl]-pyridineHCID 685761892-Pyridin-4-yl-1-(4-triisopropylsilanyloxymethyl-phenyl)-ethanone

生成物 1

HCID 685782264-[1-Methyl-3-(4-triisopropylsilanyloxymethyl-phenyl)-1H-pyrazol-4-yl]-pyridine

実験手順

Following the procedure for the preparation of 4-[3-(4-Benzyloxy-phenyl)-1-methyl-1H-pyrazol-4-yl]-pyridine but substituting 2-Pyridin-4-yl-1-(4-triisopropylsilanyloxymethyl-phenyl)-ethanone provided the title compound. MS: (M+H m/z=422.2).

出典と根拠

ORDレコード
ord-b7ac4d9ba17f441db657dccb78cb1c73
出典データセット
uspto-grants-2010_11
特許番号
US07825254B2

反応ノート

読み込み中…