Cesium carbonate → 2,6-Difluoro-4-(3,3,5-trimethyl-2,4-dioxopyrrolidin-1-yl)benzonitrile

反応式

Br[C:2]1[CH:9]=[C:8]([F:10])[C:5]([C:6]#[N:7])=[C:4]([F:11])[CH:3]=1.[CH3:12][C:13]1([CH3:21])[C:17](=[O:18])[CH:16]([CH3:19])[NH:15][C:14]1=[O:20].C(=O)([O-])[O-].[Cs+].[Cs+].C1(P(C2C=CC=CC=2)C2C3OC4C(=CC=CC=4P(C4C=CC=CC=4)C4C=CC=CC=4)C(C)(C)C=3C=CC=2)C=CC=CC=1>C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.[Pd].[Pd]>[F:10][C:8]1[CH:9]=[C:2]([N:15]2[CH:16]([CH3:19])[C:17](=[O:18])[C:13]([CH3:21])([CH3:12])[C:14]2=[O:20])[CH:3]=[C:4]([F:11])[C:5]=1[C:6]#[N:7]