Ethanol → HCID 10909830、化合物
反応式
Cl[C@H:2]([C@H:8]([OH:12])[CH2:9][CH2:10][CH3:11])[C:3]([O:5][CH2:6][CH3:7])=[O:4].C(O)C.C(=O)([O-])[O-].[K+].[K+]>C(OC)(C)(C)C>[CH2:9]([C@H:8]1[O:12][C@@H:2]1[C:3]([O:5][CH2:6][CH3:7])=[O:4])[CH2:10][CH3:11]参加物
5
反応条件
- 温度
- 15 °C
実験手順
Ethyl (2R,3R)-2-chloro-3-hydroxyhexanoate (1.0 g, 5 mmol), ethanol (10 ml) and potassium carbonate (2.1 g, 15 mmol) were mixed, and the mixture was stirred at 15° C. for 14 hours. Methyl tert-butyl ether (20 ml) was added. The mixture was washed with water (10 ml) three times. The organic layer was concentrated under reduced pressure to obtain the title compound (0.83 g, yield: 100%).
後処理
- washThe mixture was washed with water (10 ml) three times
- concentrationThe organic layer was concentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-a0e2ece933e3448495c9834afd1870b6
- 出典データセット
- uspto-grants-2010_11
- 特許番号
- US07834190B2
反応ノート
読み込み中…