1-Butanaminium, N,N,N-tributyl-, azide → HCID 10057735、化合物

HRID 1174395

反応式

HRID 1174395 の反応式
FC(F)(F)S(O[C@@H:7]1[C:11]([CH3:13])([CH3:12])[CH2:10][O:9][C:8]1=[O:14])(=O)=O.[N-:17]=[N+:18]=[N-:19].C([N+](CCCC)(CCCC)CCCC)CCC>C1(C)C=CC=CC=1.CCOCC>[N:17]([C@H:7]1[C:11]([CH3:13])([CH3:12])[CH2:10][O:9][C:8]1=[O:14])=[N+:18]=[N-:19]

参加物

5

反応物 2

HCID 57432321-Butanaminium, N,N,N-tributyl-, azideHCID 10106752(R)-4,4-dimethyl-2-oxotetrahydrofuran-3-yl trifluoromethanesulfonate

生成物 1

HCID 10057735HCID 10057735、化合物

試薬・触媒・溶媒 2

HCID 1140Toluene溶媒HCID 3283Diethyl Ether溶媒

実験手順

To a solution containing the product from Example 174A (4.6 g, 17.56 mmol) in toluene (80.0 mL) was added tetra-n-butylammonium azide (5.0 g, 17.57 mmol) at room temperature, and the mixture was stirred for 5 hours. The reaction was diluted with ether and washed with water, dilute NaHCO3, 10% citric acid and brine. The organic layer was dried over MgSO4, filtered and concentrated to give the crude product, which was used without further purification (2.79 g).

後処理

  1. washwashed with water, dilute NaHCO3, 10% citric acid and brine
  2. dry with materialThe organic layer was dried over MgSO4
  3. filtrationfiltered
  4. concentrationconcentrated

出典と根拠

ORDレコード
ord-a5df6eee4331436b851fd7a0e0d03686
出典データセット
uspto-grants-2010_11
特許番号
US07834043B2

関連ノート

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