化工社化工社 化学情報印刷レポート · 研究参考用
2-Chloromethyl 2-(trimethylsilyl)ethyl ether → Methyl 2-(3-methoxypropyl)-1-(2-trimethylsilanylethoxymethyl)-1H-benzoimidazole-4-carboxylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Chloromethyl 2-(trimethylsilyl)ethyl ether | HCID 2724271 | — |
| 反応物 | HCID 178494907 | HCID 178494907 | — |
| 生成物 | Methyl 2-(3-methoxypropyl)-1-(2-trimethylsilanylethoxymethyl)-1H-benzoimidazole-4-carboxylate | HCID 68502641 | — |
反応手順
Analogously to Example 228e, 4.3 g of methyl 2-(3-methoxypropyl)-3H-benzoimidazole-4-carboxylate and 3.54 ml of (2-chloromethoxyethyl)trimethylsilane are reacted. The title compound is obtained as a brown solid. Rf=0.33 (95:5 dichloromethane-methanol); Rt=4.26.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07842688B2 |
| 出典データセット | uspto-grants-2010_11 |
| ORD ID | ord-f5e0bfe3e4884d15a1af62f0d51bd9a5 |
| 出典メモ | uspto-grants-2010_11 |