2-Chloro-4-Phenylphenol → 3-(3-Chloro-biphenyl-4-yloxymethyl)-benzoic acid

反応式

[Cl:1][C:2]1[CH:7]=[C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:5]=[CH:4][C:3]=1[OH:14].C[O:16][C:17](=[O:26])[C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([CH2:24]Br)[CH:19]=1>>[Cl:1][C:2]1[CH:7]=[C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:5]=[CH:4][C:3]=1[O:14][CH2:24][C:20]1[CH:19]=[C:18]([CH:23]=[CH:22][CH:21]=1)[C:17]([OH:26])=[O:16]

参加物

反応物 2

HCID 70742-Chloro-4-Phenylphenol

HCID 517981Methyl 3-(bromomethyl)benzoate

生成物 1

HCID 113366873-(3-Chloro-biphenyl-4-yloxymethyl)-benzoic acid

実験手順

3-(3-Chloro-biphenyl-4-yloxymethyl)-benzoic acid was prepared using general procedure A from 2-chloro-4-phenylphenol (available from TCI America, Portland, Oreg.) and 3-(bromomethyl)benzoic acid methyl ester (available from Lancaster Synthesis Ltd., Morcambe, Lancashire, UK). Yield: 76 mg. Mass spectrum MH+=339.

出典と根拠

ORDレコード: ord-03a1c39a00474dd6b86840e950e27eba
出典データセット: uspto-grants-2010_11
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07842825B2

反応ノート

読み込み中…

参加物