Eosin → 2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid

HRID 1176799

反応式

HRID 1176799 の反応式
[CH:1]1[CH:6]=[C:5]([C:7]2[C:21]3[C:16](=[C:17](Br)[C:18]([O-:23])=[C:19](Br)[CH:20]=3)[O:15][C:14]3[C:8]=2[CH:9]=[C:10](Br)[C:11]([C:13]=3Br)=[O:12])[C:4]([C:27]([O-:29])=[O:28])=[CH:3][CH:2]=1.[Na+].[Na+].[Na][Na].CC1C(Br)=CC2C(C3C=CC=CC=3C(O)=O)=C3C(=C(Br)C(C(Br)=C3)=O)OC=2C=1Br>O>[CH:1]1[CH:2]=[CH:3][C:4]([C:27]([OH:29])=[O:28])=[C:5]([C:7]2[C:8]3[CH:9]=[CH:10][C:11]([OH:12])=[CH:13][C:14]=3[O:15][C:16]3[C:21]=2[CH:20]=[CH:19][C:18]([CH:17]=3)=[O:23])[CH:6]=1

参加物

5

反応物 3

HCID 11048EosinHCID 141233DisodiumHCID 20685766Eosin_Y

生成物 1

HCID 33832-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

With total consumption of the fluorescein, the bromination reaction leads to the formation of a single product, tetrabromofluorescein (4Br—F), the disodium salt of which is commercially known as Eosin Y. The final reaction mixture is diluted in water and the product is extracted from the mixture with ethyl acetate.

後処理

  1. customWith total consumption of the fluorescein
  2. customthe bromination reaction
  3. customThe final reaction mixture
  4. extractionthe product is extracted from the mixture with ethyl acetate

出典と根拠

ORDレコード
ord-056a597e74014b6f9e496c2103f8b8aa
出典データセット
uspto-grants-2010_11
特許番号
US07842826B2

関連ノート

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