Hydrochloric Acid → 4-phenyl-1H-pyrazole hydrochloride
反応式
[C:1]1([C:7]2[CH:8]=[N:9][N:10](C(C3C=CC=CC=3)(C3C=CC=CC=3)C3C=CC=CC=3)[CH:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[ClH:31]>CCOCC>[ClH:31].[C:1]1([C:7]2[CH:8]=[N:9][NH:10][CH:11]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1参加物
4
実験手順
A solution of 4-phenyl-1-trityl-1H-pyrazole (120 mg, 0.33 mmol) in Ether.HCl (10 mL) was stirred for 1 hr. The reaction mixture was then concentrated under reduced pressure to afford the residue. The residue obtained was washed with hexane to afford 44 mg (93.61%) of 4-phenyl-1H-pyrazole hydrochloride salt. 1H NMR (DMSO-d6): δ 8.1-8.08 (s, 2H), 7.64 (d, 2H), 7.38 (t, 2H), 7.22 (t, 1H).
後処理
- concentrationThe reaction mixture was then concentrated under reduced pressure
- customto afford the residue
- customThe residue obtained
- washwas washed with hexane
出典と根拠
- ORDレコード
- ord-e11280c59b4949de95b3b387c264466f
- 出典データセット
- uspto-grants-2010_11
- 特許番号
- US07842696B2
反応ノート
読み込み中…