Hydrochloric Acid → HCID 68526195、化合物
反応式
[ClH:1].[CH:2]1([C:8]2([CH2:23][S:24][CH3:25])[CH2:14][CH:13]3[N:15](C(OC(C)(C)C)=O)[CH:10]([CH2:11][CH2:12]3)[CH2:9]2)[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1>O1CCOCC1>[Cl-:1].[CH:2]1([C:8]2([CH2:23][S:24][CH3:25])[CH2:14][CH:13]3[NH2+:15][CH:10]([CH2:11][CH2:12]3)[CH2:9]2)[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7]1参加物
4
実験手順
To a solution of 4.0 N HCl in dioxane (20.0 mL) was added tert-butyl 3-cyclohexyl-3-[(methylthio)methyl]-8-azabicyclo[3.2.1]octane-8-carboxylate (3-5) (0.870 g, 2.46 mmol). The mixture was stirred at room temperature for three hours and the volatiles were removed under vacuum to give (3-6) as a pale solid.
後処理
- customthe volatiles were removed under vacuum
出典と根拠
- ORDレコード
- ord-1277d9c0b5654b00b094e10817c71cc9
- 出典データセット
- uspto-grants-2007_10
- 特許番号
- US07276520B2
反応ノート
読み込み中…