Ethyl (morpholin-4-ylcarbonothioyl)carbamate → HCID 178473535、化合物
反応式
[CH2:1]([O:3][C:4](=[O:14])[NH:5][C:6]([N:8]1[CH2:13][CH2:12][O:11][CH2:10][CH2:9]1)=S)[CH3:2].Cl.Cl.[NH2:17][CH:18]([CH2:34][CH:35]1[CH2:40][CH2:39][CH2:38][CH2:37][CH2:36]1)[C:19]([NH:21][C:22]1([C:32]#[N:33])[CH2:26][CH2:25][N:24]([CH:27]([CH2:30][CH3:31])[CH2:28][CH3:29])[CH2:23]1)=[O:20]>>[CH2:1]([O:3][C:4](=[O:14])[N:5]=[C:6]([NH:17][CH:18]([C:19](=[O:20])[NH:21][C:22]1([C:32]#[N:33])[CH2:26][CH2:25][N:24]([CH:27]([CH2:28][CH3:29])[CH2:30][CH3:31])[CH2:23]1)[CH2:34][CH:35]1[CH2:40][CH2:39][CH2:38][CH2:37][CH2:36]1)[N:8]1[CH2:13][CH2:12][O:11][CH2:10][CH2:9]1)[CH3:2]参加物
3
実験手順
The title compound was prepared starting from (Morpholine-4-carbothioyl)-carbamic acid ethyl ester and 2-amino-N-[3-cyano-1-(1-ethyl-propyl)-pyrrolidin-3-yl]-3-cyclohexyl-propionamide bis hydrochloride salt according to the procedure from Example 76, step b, MS, m/z 519=M+1.
出典と根拠
- ORDレコード
- ord-425f598eada84ec6802b29e42082e78e
- 出典データセット
- uspto-grants-2007_10