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Isovaleryl chloride → 3-Methyl-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)butanamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Isovaleryl chloride | HCID 66054 | — |
| 反応物 | 3-(2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline | HCID 49852105 | — |
| 生成物 | 3-Methyl-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)butanamide | HCID 57478285 | 64% |
反応手順
The title compound was prepared in 64% yield according to the general procedure for the preparation of the amides (Method B) starting from 3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline (D6) and 3-methylbutanoyl chloride.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07279481B2 |
| 出典データセット | uspto-grants-2007_10 |
| ORD ID | ord-0968e99ffd3c49d78ee2877a4ac6e7df |
| 出典メモ | uspto-grants-2007_10 |