4-Chlorobenzoyl chloride → HCID 178522254、化合物
反応式
[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][CH:3]=1.[NH2:11][C:12]1[CH:13]=[CH:14][C:15]([O:18]C)=[N:16][CH:17]=1>ClCCl>[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([NH:11][C:12]2[CH:17]=[N:16][C:15]([OH:18])=[CH:14][CH:13]=2)=[O:7])=[CH:4][CH:3]=1参加物
4
実験手順
4-Chlorobenzoyl chloride (1.75 g, 10.0 mmol) was added carefully to a stirred solution of 5-amino-2-methoxypyridine (1.24 g, 10.0 mmol) in dichloromethane (10 mL). After stirring overnight at room temperature, the solvent is evaporated in vacuo and the residue is heated in a pre-heated kugelrohr oven at 200° C. for 5-10 minutes under house-vacuum (around 20 mbar) yielding the title compound, which was used without further purification.
後処理
- customthe solvent is evaporated in vacuo
- temperaturethe residue is heated in a pre-heated kugelrohr oven at 200° C. for 5-10 minutes under house-vacuum (around 20 mbar)
出典と根拠
- ORDレコード
- ord-572c0c791b864b0d8f0d1968ba44657d
- 出典データセット
- uspto-grants-2007_10
- 特許番号
- US07279470B2
反応ノート
読み込み中…