Carbamic chloride, N-methyl-N-phenyl- → Methyl-phenyl-carbamic acid 4-(5-trifluoromethylpyridin-2-yloxy)-phenyl ester

HRID 1179701

反応式

HRID 1179701 の反応式
[F:1][C:2]([F:18])([F:17])[C:3]1[CH:4]=[CH:5][C:6]([O:9][C:10]2[CH:15]=[CH:14][C:13]([OH:16])=[CH:12][CH:11]=2)=[N:7][CH:8]=1.[CH3:19][N:20]([C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1)[C:21](Cl)=[O:22]>>[F:18][C:2]([F:1])([F:17])[C:3]1[CH:4]=[CH:5][C:6]([O:9][C:10]2[CH:11]=[CH:12][C:13]([O:16][C:21](=[O:22])[N:20]([CH3:19])[C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)=[CH:14][CH:15]=2)=[N:7][CH:8]=1

参加物

3

反応物 2

HCID 77969Carbamic chloride, N-methyl-N-phenyl-HCID 1552414-(5-Trifluoromethyl-pyridin-2-yloxy)-phenol

生成物 1

HCID 10150601Methyl-phenyl-carbamic acid 4-(5-trifluoromethylpyridin-2-yloxy)-phenyl ester

実験手順

The title compound was prepared from 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenol and N-methyl-N-phenylcarbamoyl chloride. The crude product was purified by preparative HPLC (36%, white crystals). HPLC-MS m/z=389.1 (M+1), Rt: 5.13 min.

後処理

  1. customThe crude product was purified by preparative HPLC (36%, white crystals)

出典と根拠

ORDレコード
ord-60001a5ea9c441f782c4b0c1679e62fa
出典データセット
uspto-grants-2007_10
特許番号
US07279470B2

関連ノート

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