1-methyl-3-(methyl-phenyl-carbamoyl)-3H-imidazol-1-ium iodide → Methyl-phenyl-carbamic Acid 4-(4,4-dimethyl-2,6-dioxo-piperidin-1-yl)-phenyl Ester

HRID 1179728ノート

反応式

HRID 1179728 の反応式
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:13](=[O:14])[CH2:12][C:11]([CH3:16])([CH3:15])[CH2:10][C:9]2=[O:17])=[CH:4][CH:3]=1.[I-].C[N+]1C=CN([C:25](=[O:34])[N:26]([CH3:33])[C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=2)C=1>>[CH3:16][C:11]1([CH3:15])[CH2:10][C:9](=[O:17])[N:8]([C:5]2[CH:4]=[CH:3][C:2]([O:1][C:25](=[O:34])[N:26]([CH3:33])[C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=3)=[CH:7][CH:6]=2)[C:13](=[O:14])[CH2:12]1

参加物

3

反応物 2

HCID 109478841-methyl-3-(methyl-phenyl-carbamoyl)-3H-imidazol-1-ium iodideHCID 220477421-(4-Hydroxyphenyl)-4,4-dimethylpiperidine-2,6-dione

生成物 1

HCID 10126229Methyl-phenyl-carbamic Acid 4-(4,4-dimethyl-2,6-dioxo-piperidin-1-yl)-phenyl Ester

実験手順

The title product was prepared from 1-(4-hydroxyphenyl)-4,4-dimethylpiperidine-2,6-dione (233 mg, 1.00 mmol)) and 1-methyl-3-(methyl-phenyl-carbamoyl)-3H-imidazol-1-ium iodide (343 mg, 1.00 mmol) by applying general procedure 3 (192 mg, 52%, white solid). HPLC-MS m/z=367 (M+1); Rt=3.78 min.

出典と根拠

ORDレコード
ord-cf892264fe564264a1f845f2b6f77eb3
出典データセット
uspto-grants-2007_10
特許番号
US07279470B2

反応ノート

読み込み中…