1,2,3,4-Tetrahydroisoquinoline → N-(3-tert-Butyl-phenyl)-6-(3,4-dihydro-1H-isoquinolin-2-yl)-nicotinamide

反応式

[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][c:7]([NH:11][C:12]([c:13]2[cH:14][n:15][c:16]([Cl:19])[cH:17][cH:18]2)=[O:20])[cH:8][cH:9][cH:10]1.[CH2:21]1[NH:22][CH2:23][CH2:24][c:25]2[cH:26][cH:27][cH:28][cH:29][c:30]21.[I:31][c:32]1[cH:33][c:34]([NH:35][C:36](=[O:37])[c:38]2[cH:39][cH:40][c:41]([N:42]3[CH2:43][CH2:44][O:45][CH2:46][CH2:47]3)[n:48][cH:49]2)[cH:50][cH:51][c:52]1[CH3:53]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][c:7]([NH:11][C:12]([c:13]2[cH:14][n:15][c:16]([N:22]3[CH2:21][c:30]4[c:25]([cH:26][cH:27][cH:28][cH:29]4)[CH2:24][CH2:23]3)[cH:17][cH:18]2)=[O:20])[cH:8][cH:9][cH:10]1