関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Sulfuric Acid | HCID 1118 | — |
| 反応物 | Acetonitrile | HCID 6342 | — |
| 反応物 | cis-1,2-Indandiol | HCID 20758 | — |
| 生成物 | (1R,2S)-(+)-cis-1-Amino-2-indanol | HCID 2725045 | — |
反応手順
Cis-1,2-indandiol (1.0 g) was dissolved in acetonitrile (20 mL), cooled to -40° C., and fuming sulfuric acid (21% SO3, 0.8 mL) was added. The mixture was aged for 1 hour with gradual warming to 0° C. Water was added and the mixture heated to 80° C. for 1 hour to provide an aqueous solution of cis-1-amino-2-indanol.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05723615 |
|---|
| 出典データセット | uspto-grants-1998_03 |
|---|
| ORD ID | ord-bb4572950e154c0d8d7ae87ec0fb230d |
|---|
| 出典メモ | uspto-grants-1998_03 |
|---|
