tert-Butylhydrazine monohydrochloride → 1-tert-butyl-3-(4-nitrophenyl)-1H-pyrazole

反応式

C[C:2]([CH:5]([N:9]1[CH:13]=[C:12](B2OC(C)(C)C(C)(C)O2)[C:11]([C:23]2[CH:28]=[CH:27][C:26]([N+:29]([O-:31])=[O:30])=[CH:25][CH:24]=2)=[N:10]1)[C:6]([O-])=O)(C)C.Cl.[C:33](NN)(C)(C)C>>[CH3:33][C:5]([N:9]1[CH:13]=[CH:12][C:11]([C:23]2[CH:24]=[CH:25][C:26]([N+:29]([O-:31])=[O:30])=[CH:27][CH:28]=2)=[N:10]1)([CH3:2])[CH3:6]

参加物

反応物 2

HCID 81889tert-Butylhydrazine monohydrochloride

HCID 69001014HCID 69001014、化合物

生成物 1

HCID 534855281-tert-butyl-3-(4-nitrophenyl)-1H-pyrazole

実験手順

Following the procedure described for Intermediate 1 with t-butylhydrazine hydrochloride, provided the title compound as the minor isomer. ESMS (M−C(CH3)3+2H): 190.0; HNMR (400 MHz, d6-DMSO)8.20 (d, 2H), 7.86 (d, 2H), 7.7(d, 1H), 6.55(d, 1H), 1.25 (s, 9H)

出典と根拠

ORDレコード: ord-ae0323dd21a246e9abe16cce46e56390
出典データセット: uspto-grants-2007_10
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07282588B2

反応ノート

読み込み中…