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HRID 1181749作成日：2026年10月26日

1-Methyl-2-imidazolecarboxaldehyde → 7-isobutyl-5-methyl-3-(1-methyl-1H-imidazol-2-yl)-2-[(5-nitro-1H-indol-3-yl)methyl]-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

https://huagongshe.com/reaction/1181749

反応式

関与物質

役割名称HCID仕込み量
反応物1-Methyl-2-imidazolecarboxaldehydeHCID 139575—
反応物5-nitro-1H-indole-3-carbaldehydeHCID 246039—
反応物6-hydrazino-1-isobutyl-3-methyl-2,4(1H,3H)-pyrimidinedioneHCID 19356084—
生成物7-isobutyl-5-methyl-3-(1-methyl-1H-imidazol-2-yl)-2-[(5-nitro-1H-indol-3-yl)methyl]-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dioneHCID 58981145—

反応手順

This compound was made following the procedure described above, starting with 6-hydrazino-1-isobutyl-3-methylpyrimidine-2,4(1H,3H)-dione, and condensing first with 5-nitro-1H-indole-3-carbaldehyde, followed by 1-methyl-1H-imidazole-2-carbaldehyde. Mass: 477.19 (M+H).

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07285558B2
出典データセットuspto-grants-2007_10
ORD IDord-13e52587452f4ec28581a223e2049c83
出典メモuspto-grants-2007_10