1-Ethyl-2-pyrrolecarboxaldehyde → 2-[(5-chloro-1H-indol-3-yl)methyl]-3-(1-ethyl-1H-pyrrol-2-yl)-7-isobutyl-5-methyl-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione
反応式
[NH:1]([C:3]1[N:8]([CH2:9][CH:10]([CH3:12])[CH3:11])[C:7](=[O:13])[N:6]([CH3:14])[C:5](=[O:15])[CH:4]=1)[NH2:2].[Cl:16][C:17]1[CH:18]=[C:19]2[C:23](=[CH:24][CH:25]=1)[NH:22][CH:21]=[C:20]2[CH:26]=O.[CH2:28]([N:30]1[CH:34]=[CH:33][CH:32]=[C:31]1[CH:35]=O)[CH3:29]>>[Cl:16][C:17]1[CH:18]=[C:19]2[C:23](=[CH:24][CH:25]=1)[NH:22][CH:21]=[C:20]2[CH2:26][N:2]1[C:35]([C:31]2[N:30]([CH2:28][CH3:29])[CH:34]=[CH:33][CH:32]=2)=[C:4]2[C:3]([N:8]([CH2:9][CH:10]([CH3:11])[CH3:12])[C:7](=[O:13])[N:6]([CH3:14])[C:5]2=[O:15])=[N:1]1参加物
4
反応物 3
生成物 1
実験手順
This compound was made following the procedure described above, starting with 6-hydrazino-1-isobutyl-3-methylpyrimidine-2,4(1H,3H)-dione and condensing first with 5-chloro-1H-indole-3-carbaldehyde, followed by 1-ethyl-1H-pyrrole-2-carbaldehyde. 479 (M+H).