Acetic Anhydride → 7-Methoxyisochroman-1,3-dione
反応式
[O:1]([C:3]1[CH:4]=[C:5]([C:13]([OH:15])=[O:14])[C:6](=[CH:11][CH:12]=1)[CH2:7][C:8]([OH:10])=O)[CH3:2].C(OC(=O)C)(=O)C>C1(C)C=CC=CC=1>[O:1]([C:3]1[CH:4]=[C:5]2[C:13](=[O:14])[O:15][C:8](=[O:10])[CH2:7][C:6]2=[CH:11][CH:12]=1)[CH3:2]参加物
4
実験手順
1.1 g (5.2 mmol) of 4-methoxylhomophthalic acid (IIb) was dissolved in 20 ml toluene, and 0.7 ml (7.9 mmol) of acetic anhydride was added. The mixture was heated to the reflux temperature and reacted for 0.5 h. Then, the reaction mixture was cooled to the room temperature and concentrated to dry in a reduced pressure to obtain 1.1 g of a pale yellow solid with the yield of 100%. m.p. 142-143° C.
後処理
- temperatureThe mixture was heated to the reflux temperature
- customreacted for 0.5 h
- concentrationconcentrated
- customto dry in a reduced pressure
出典と根拠
- ORDレコード
- ord-0e854e3c0041495d83017d510ade7a4a
- 出典データセット
- uspto-grants-2014_03
- 特許番号
- US08664238B2
反応ノート
読み込み中…