[CH3:1][O:2][C:3]([C:5]1[CH:9]=[C:8]([OH:10])[N:7]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=2[F:17])[N:6]=1)=[O:4].[C:18]1(P(C2C=CC=CC=2)C2C=CC=CC=2)[CH:23]=CC=C[CH:19]=1.CC(O)C.N(C(OCC1C=CC(Cl)=CC=1)=O)=NC(OCC1C=CC(Cl)=CC=1)=O>C(Cl)Cl>[F:17][C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][C:11]=1[N:7]1[C:8]([O:10][CH:18]([CH3:23])[CH3:19])=[CH:9][C:5]([C:3]([O:2][CH3:1])=[O:4])=[N:6]1150 mg (0.635 mmol) of 1-(2-fluoro-phenyl)-5-hydroxy-1H-pyrazole-3-carboxylic acid methyl ester, 166.6 mg (0.635 mmol) of triphenylphosphine and 38.16 mg (0.635 mmol) of 2-propanol were dissolved in 1.5 ml of DCM, and then a solution of 0.635 mmol of di(4-chlorobenzyl) azodicarboxylate in 1.5 ml of DCM was added. After stirring at room temperature for 4 h, the mixture was filtered and the solvent removed in vacuo. The obtained crude title compound was used in the hydrolysis step without further purification.
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