Dihydro-8-methyl-2H-1,4-benzoxazine-2-carboxamide → Dihydro-8-methyl-2H-1,4-benzoxazine-2-methanamine

反応式

FC1C2OC(CN)CNC=2C=CC=1.[CH3:14][C:15]1[C:24]2[O:23][CH:22]([C:25]([NH2:27])=O)[CH2:21][NH:20][C:19]=2[CH:18]=[CH:17][CH:16]=1>>[CH3:14][C:15]1[C:24]2[O:23][CH:22]([CH2:25][NH2:27])[CH2:21][NH:20][C:19]=2[CH:18]=[CH:17][CH:16]=1

参加物

反応物 2

HCID 67497427Dihydro-8-methyl-2H-1,4-benzoxazine-2-carboxamide

HCID 67497870Dihydro-8-fluoro-2H-1,4-benzoxazine-2-methanamine

生成物 1

HCID 67498071Dihydro-8-methyl-2H-1,4-benzoxazine-2-methanamine

実験手順

This compound is obtained using the same experimental conditions as those used for the synthesis of intermediate 2b but by replacing 3,4-dihydro-8-fluoro-2H-1,4-benzoxazine-2-carboxamide (4b) with 3,4-dihydro-8-methyl-2H-1,4-benzoxazine-2-carboxamide (4c). The title compound of formula (2c) is obtained.

後処理

customThis compound is obtained

出典と根拠

ORDレコード: ord-bb69e053b920402581cdc48e7e79ae79
出典データセット: uspto-grants-2014_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08669250B2

反応ノート

読み込み中…

参加物