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HRID 1184359作成日：2026年10月27日

3-Amino-2-hydroxybenzonitrile → Dihydro-8-cyano-2H-1,4-benzoxazine-2-methanamine

https://huagongshe.com/reaction/1184359

反応式

関与物質

役割名称HCID仕込み量
反応物3-Amino-2-hydroxybenzonitrileHCID 12468681—
反応物Dihydro-8-fluoro-2H-1,4-benzoxazine-2-methanamineHCID 67497870—
生成物Dihydro-8-cyano-2H-1,4-benzoxazine-2-methanamineHCID 67497003—

反応手順

This compound is obtained using the same reaction sequence and the same experimental conditions as those used for the synthesis of intermediate 2b but replacing 2-amino-6-fluorophenol with 2-amino-6-cyanophenol. The title compound of formula (2f) is obtained.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08669250B2
出典データセットuspto-grants-2014_03
ORD IDord-f59af44eaafe4455970022d0d05fc476
出典メモuspto-grants-2014_03