化工社化工社 化学情報印刷レポート · 研究参考用
3-Chloro-4-fluorobenzoic acid → 3-chloro-4-fluoro-N-isopropylbenzamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Chloro-4-fluorobenzoic acid | HCID 520989 | — |
| 反応物 | 2-Propanamine, hydrochloride (1:1) | HCID 6432137 | — |
| 生成物 | 3-chloro-4-fluoro-N-isopropylbenzamide | HCID 58324493 | — |
反応手順
Using isopropylamine hydrochloride and 3-chloro-4-fluorobenzoic acid in the general procedure for coupling of amines to carboxylic acids, the title compound was obtained as a white solid (81% yield). ESI-MS: m/z 216 (M+H)+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08669249B2 |
| 出典データセット | uspto-grants-2014_03 |
| ORD ID | ord-b6623b9069534d28a5ebf78d10498bef |
| 出典メモ | uspto-grants-2014_03 |