Phenol → HCID 86664216、化合物

反応式

[F:1][C:2]1[CH:9]=[C:8]([OH:10])[C:7]([N+:11]([O-:13])=[O:12])=[CH:6][C:3]=1[CH:4]=[O:5].C1(O)C=CC=CC=1.[CH3:21][O:22][C:23](=[O:27])[CH:24](Br)[CH3:25]>>[F:1][C:2]1[C:3]([CH:4]=[O:5])=[CH:6][C:7]([N+:11]([O-:13])=[O:12])=[C:8]([CH:9]=1)[O:10][CH:24]([CH3:25])[C:23]([O:22][CH3:21])=[O:27]

参加物

反応物 3

HCID 996Phenol

HCID 95576Methyl 2-bromopropionate

HCID 866642172-Fluoro-4-hydroxy-5-nitro-benzaldehyde

生成物 1

HCID 86664216HCID 86664216、化合物

実験手順

Using 2-fluoro-4-hydroxy-5-nitrobenzaldehyde as the phenol and methyl-2-bromopropanoate as the alkylating agent in the general procedure for alkylation of substituted-2-nitrophenols gives the title compound as a white solid: ESI-MS: m/z 272.1 (M+H)+.

出典と根拠

ORDレコード: ord-b1f3d70c2d9c42eeb02e26e5aa85d878
出典データセット: uspto-grants-2014_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08669249B2

反応ノート

読み込み中…