Glufosinate → HCID 178476818、化合物

HRID 1184981

反応式

HRID 1184981 の反応式
C[P:2]([OH:11])([CH2:4][CH2:5][CH:6](N)C(O)=O)=[O:3].P(Cl)(Cl)Cl.[Cl-:16].[Cl-].[Cl-].[Cl-].[Al+3].[CH2:21]=[CH2:22]>C(O)C>[Cl:16][CH2:6][CH2:5][CH2:4][PH:2](=[O:3])[O:11][CH2:21][CH3:22]

参加物

6

反応物 4

HCID 4794GlufosinateHCID 6325EthyleneHCID 24387Phosphorus trichlorideHCID 25114082Aluminum tetrachloride

生成物 1

HCID 178476818HCID 178476818、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

Alternatively, another method of producing glufosinate generally comprises converting phosphorus trichloride to an adduct of methylphosphonous trichloride and aluminum tetrachloride (i.e., CH3PCl3.AlCl4). The adduct may be reacted with ethylene to form an intermediate adduct, which then may be reacted with ethanol to form ethyl 1-(2-chloroethyl)-methylphosphinate. Ethyl 1-(2-chlorethyl)-methylphosphinate may then be reacted with potassium hydroxide and ethanol to prepare the requisite ethyl vinylphosphinate precursor. The ethyl vinylphosphinate precursor is subjected to hydroformylation-aminocarbonylation, followed by hydrolysis of the hydroformylation-aminocarbonylation product in the presence of hydrochloric acid to produce glufosinate.

後処理

  1. customto form an intermediate adduct, which

出典と根拠

ORDレコード
ord-b7d56bc03a6b4088809a1fff735d8036
出典データセット
uspto-grants-2014_03
特許番号
US08669396B2

関連ノート

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