Sebacoyl chloride → decanedioic acid bis[1-(N,N'-dicyclohexyl-carbamimidoyloxy)-2,2,6,6-tetramethyl-piperidin-4-yl]ester

関与物質

反応手順

To a solution of 1,3-dicyclohexyl-2-(4-hydroxy-2,2,6,6-tetramethyl-piperidin-1-yl)-isourea [compound 8 prepared according to Example 8] (8.35 g, 22 mmol) and 4-dimethylaminopyridine (160 mg) in pyridine (20 ml) is added sebacoylchloride (2.5 g, 10.5 mmol). The mixture is stirred at room temperature for 22 hours and then diluted with ice-water (250 ml). The precipitate is filtered off, washed with water and dried to afford 9.75 g of the title compound as an off-white solid.

情報源と証拠