2-Isopropyl-3,6-dimethoxy-5-[2-(2,2,2-trifluoro-ethoxy)-ethyl]-2,5-dihydropyrazine → 2-Methoxycarbonylamino-4-(2,2,2-trifluoro-ethoxy)-butyric acid methyl ester
反応式
[CH3:1][O:2][C:3](=[O:16])[CH:4]([NH:11][C:12]([O:14][CH3:15])=[O:13])[CH2:5][CH2:6]C(F)(F)F.C(C1C(OC)=NC(CC[O:30][CH2:31][C:32]([F:35])([F:34])[F:33])C(OC)=N1)(C)C>>[CH3:1][O:2][C:3](=[O:16])[CH:4]([NH:11][C:12]([O:14][CH3:15])=[O:13])[CH2:5][CH2:6][O:30][CH2:31][C:32]([F:35])([F:34])[F:33]参加物
3
実験手順
This compound was made by the same procedure as 5,5,5-Trifluoro-2-methoxycarbonylamino-pentanoic acid methyl ester, using 2-Isopropyl-3,6-dimethoxy-5-[2-(2,2,2-trifluoro-ethoxy)-ethyl]-2,5-dihydropyrazine as the starting material. 1H-NMR: 400 MHz, (CDCl3) δ: 5.51-5.43 (br, 1H), 4.51-4.43 (m, 1H), 3.83-3.63 (m, 10H), 2.22-2.13 (m, 1H), 2.13-2.03 (m, 1H) ppm.
出典と根拠
- ORDレコード
- ord-2556821606be46c988fb74caace4972d