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HRID 11860作成日:2026年10月26日

Diethylamine → (2S)-2-amino-5-(((tert-butoxy)carbonyl)amino)pentanoic acid

https://huagongshe.com/reaction/11860

反応式

関与物質

役割名称HCID仕込み量
反応物DiethylamineHCID 8021—
反応物(2S)-5-(((tert-butoxy)carbonyl)amino)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)pentanoic acidHCID 2756114—
溶媒DimethylformamideHCID 6228—
生成物(2S)-2-amino-5-(((tert-butoxy)carbonyl)amino)pentanoic acidHCID 6993436210%

反応手順

The compound obtained in Example 23-1 (250.8 mg) was dissolved in DMF (5 ml). After the addition of diethylamine. (0.5 ml), the mixture was stirred for 2 hours at room temperature. After the reaction, the solvent was removed by distillation under reduced pressure and the residue was dried under vacuum to obtain the title compound (269.1 mg).

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07098215B2
出典データセットuspto-grants-2006_08
ORD IDord-4dc70e910fce4c9ba040b32abaa97152
出典メモuspto-grants-2006_08