化工社化工社 化学情報印刷レポート · 研究参考用
Potassium Carbonate → N-(3-chloroquinoxalin-2-yl)-2-fluorobenzenesulfonamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | 2,3-Dichloroquinoxaline | HCID 16659 | — |
| 反応物 | 2-Fluorobenzenesulfonamide | HCID 193663 | — |
| 溶媒 | Dimethyl Sulfoxide | HCID 679 | — |
| 生成物 | N-(3-chloroquinoxalin-2-yl)-2-fluorobenzenesulfonamide | HCID 86657929 | 75% |
反応手順
According to Reference Example 6-1, by use of 2,3-dichloroquinoxaline (80 mg, 0.40 mmol), dimethyl sulfoxide (2 mL), 2-fluorobenzenesulfonamide (70 mg, 0.40 mmol) and potassium carbonate (56 mg, 0.40 mmol), the mixture was stirred and reacted at 150° C. for 1.5 hours. Thus, N-(3-chloroquinoxalin-2-yl)-2-fluorobenzenesulfonamide (Compound AE) (101 mg, yield: 75%) was obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08673908B2 |
| 出典データセット | uspto-grants-2014_03 |
| ORD ID | ord-13da6086a4ae41d0b7a6d7e9b4af0ba8 |
| 出典メモ | uspto-grants-2014_03 |