Ammonia → 4-Ethyl-7-(4-nitro-phenylazo)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ol

HRID 1190779ノート

反応式

HRID 1190779 の反応式
F[B-](F)(F)F.[N+:6]([C:9]1[CH:14]=[CH:13][C:12]([N+:15]#[N:16])=[CH:11][CH:10]=1)([O-:8])=[O:7].[CH2:17]([N:19]1[C:24]2[CH:25]=[C:26]([OH:29])[CH:27]=[CH:28][C:23]=2[O:22][CH2:21][CH2:20]1)[CH3:18].N>S(=O)(=O)(O)O>[CH2:17]([N:19]1[C:24]2[CH:25]=[C:26]([OH:29])[C:27]([N:16]=[N:15][C:12]3[CH:11]=[CH:10][C:9]([N+:6]([O-:8])=[O:7])=[CH:14][CH:13]=3)=[CH:28][C:23]=2[O:22][CH2:21][CH2:20]1)[CH3:18]

参加物

5

反応物 3

HCID 222AmmoniaHCID 680064-Nitrobenzenediazonium tetrafluoroborateHCID 687776134-Ethyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-ol

生成物 1

HCID 1363315334-Ethyl-7-(4-nitro-phenylazo)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ol

試薬・触媒・溶媒 1

HCID 1118Sulfuric Acid溶媒

実験手順

p-Nitrobenzenediazonium tetrafluoroborate (0.251 g, 1.06 mmol) was dissolved in 10% sulfuric acid (10 ml) and added to a methanolic solution (10 ml) of 50a (0.19 g, 1.06 mmol). The solution turned red immediately. The reaction mixture was neutralized with ammonia. The red precipitate was filtered to give quantitative yield of the product. ES-HRMS [M−H]− 327.1428. Calcd for (C16H15N4O4): 327.1094.

後処理

  1. filtrationThe red precipitate was filtered

出典と根拠

ORDレコード
ord-3f8f00a583894ec9a8897db4f9fb689d
出典データセット
uspto-grants-2014_03
特許番号
US08679776B2

反応ノート

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