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2-Chloro-6-methylnicotinic acid → 5-[1,2,3]Triazol-2-yl-benzo[1,3]dioxole-4-carboxylic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Chloro-6-methylnicotinic acid | HCID 121724 | — |
| 反応物 | 5-Bromobenzo(1,3)dioxole-4-carboxylic acid | HCID 12514106 | — |
| 反応物 | 6-Methyl-2-[1,2,3]triazol-2-yl-nicotinic acid | HCID 67086855 | — |
| 生成物 | 5-[1,2,3]Triazol-2-yl-benzo[1,3]dioxole-4-carboxylic acid | HCID 67116281 | — |
反応手順
The title compound was prepared in a manner analogous to Intermediate 47 substituting 5-bromobenzo[1,3]dioxole-4-carboxylic acid for 2-chloro-6-methylnicotinic acid. MS (ESI): mass calculated for C10H7N3O4, 233.18; m/z found 234.3 [M+H]+. 1H NMR (400 MHz, CD3OD): 7.85 (s, 2H), 7.23 (d, J=8.4 Hz, 1H), 7.04 (d, J=8.4 Hz, 1H), 6.16 (s, 2H).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08680275B2 |
| 出典データセット | uspto-grants-2014_03 |
| ORD ID | ord-f46c621487014487b4d4699a832d4251 |
| 出典メモ | uspto-grants-2014_03 |