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Ethanol → 4-(4-Pentenoxy)-4'-nitrobiphenyl
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethanol | HCID 702 | — |
| 反応物 | Potassium Hydroxide | HCID 14797 | — |
| 反応物 | 1-Pentene, 5-bromo- | HCID 70704 | — |
| 反応物 | 4-Hydroxy-4'-nitrobiphenyl | HCID 138078 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 4-(4-Pentenoxy)-4'-nitrobiphenyl | HCID 19901284 | — |
反応手順
To 400 ml ethanol is added 21.5 g of 4-hydroxy-4'nitrobiphenyl, and the mixture heated to reflux. A solution of 7.1 g KOH in 30 ml of water is added dropwise at reflux temperatures. After complete addition, 18 g of 5-bromo-1-pentene is added and the reaction medium is heated at reflux temperature for about 15 hours. Ethanol is removed under vacuum from the cooled mixture, and the solid residue is slurried with water in a blender, filtered, washed with water, and air dried. The product then is recrystallized from 90/10 hexane/toluene, mp 74°-76° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04810338 |
| 出典データセット | uspto-grants-1989_03 |
| ORD ID | ord-da7580f119a24001b8b72f67536987e9 |
| 出典メモ | uspto-grants-1989_03 |