化工社化工社 化学情報印刷レポート · 研究参考用
Toluene → Chrysene-2-carbaldehyde
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Toluene | HCID 1140 | — |
| 反応物 | 2-Hydroxymethylchrysene | HCID 15599323 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | Chrysene-2-carbaldehyde | HCID 15599322 | 88% |
反応手順
2-Hydroxymethylchrysene (20C, 8.0 g, 0.031 mol) in CH2Cl2 (2.5 L) was treated with BaMnO4 (Aldrich, 15.9 g, 0.062 mol) and refluxed for 12 h. The reaction mixture was filtered, and concentrated to give a solid, which was then passed through a plug of SiO2 (500 g) using PhCH3 as the eluting solvent. The appropriate fractions were combined and the volume reduced to 75 mL to afford 6.98 g (88%) of chrysene-2-carbaldehyde mp 215°-216.5°, (C, H).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04810727 |
| 出典データセット | uspto-grants-1989_03 |
| ORD ID | ord-23a8089684ec47f5ba642666851d932d |
| 出典メモ | uspto-grants-1989_03 |