Benzylamine → Benzeneacetamide, 4-hydroxy-N-(phenylmethyl)-

HRID 1193997ノート

反応式

HRID 1193997 の反応式
CO[C:3](=[O:12])[CH2:4][C:5]1[CH:10]=[CH:9][C:8]([OH:11])=[CH:7][CH:6]=1.[CH2:13]([NH2:20])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[CH2:13]([NH:20][C:3](=[O:12])[CH2:4][C:5]1[CH:6]=[CH:7][C:8]([OH:11])=[CH:9][CH:10]=1)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

参加物

3

反応物 2

HCID 7504BenzylamineHCID 518900Benzeneacetic acid, 4-hydroxy-, methyl ester

生成物 1

HCID 8376026Benzeneacetamide, 4-hydroxy-N-(phenylmethyl)-

実験手順

A mixture of 80 g of 4-hydroxyphenylacetic acid methyl ester and 51.6 g of benzylamine is brought to 180° C. for 8 hours. The mixture is allowed to return to room temperature and the crystals are filtered off and washed with ethanol and then ethyl ether.

後処理

  1. customto return to room temperature
  2. filtrationthe crystals are filtered off
  3. washwashed with ethanol

出典と根拠

ORDレコード
ord-e6cc62827f5340b38cecc8f52ef224c7
出典データセット
uspto-grants-1989_03
特許番号
US04812469

反応ノート

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