HCID 15615543、化合物 → HCID 178419539、化合物
反応式
[CH3:1][N:2]([CH3:14])[C:3]([C:5]1[O:6][C:7]([C:10](=O)[CH2:11][Br:12])=[CH:8][CH:9]=1)=[O:4].[CH2:15]([NH:21][C:22]([NH:24][C:25]([NH2:27])=[S:26])=[NH:23])[CH2:16][CH2:17][CH2:18][CH2:19][CH3:20]>CC(C)=O>[BrH:12].[CH2:15]([NH:21][C:22](=[NH:23])[NH:24][C:25]1[S:26][CH:11]=[C:10]([C:7]2[O:6][C:5]([C:3](=[O:4])[N:2]([CH3:14])[CH3:1])=[CH:9][CH:8]=2)[N:27]=1)[CH2:16][CH2:17][CH2:18][CH2:19][CH3:20]参加物
4
実験手順
A mixture of 2.6 g. (0.01 mole) of N,N-dimethyl5-(2-bromoacetyl)furan-2-carboxamide, 2.02 g. (0.01 mole) of (N-n-hexylguanyl)thiourea and 75 ml. of acetone was heated under reflux for 4 hours, and then it was cooled and filtered. This gave 2.3 g. of the title compound as a white solid, mp. 155°-158° C.
後処理
- additionA mixture of 2.6 g
- temperatureunder reflux for 4 hours