関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | (2,3-Dihydroxypropyl)trimethylammonium chloride | HCID 161796 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | (3-Chloro-2-hydroxypropyl)trimethylammonium chloride | HCID 18732 | 96.6% |
反応手順
There was suspended 9.20 g of 2,3-dihydroxypropyltrimethylammonium chloride (chemical purity: 100%) in 50 ml of dimethylformamide, and thereto 6.80 g of thionyl chloride was added at a temperature from 5° to 10° C. After stirring for 20 minutes, it was heated at 100° C. for 5 hours. Finally, after cooling the reaction mixture to room temperature, 9.85 g of 3-chloro-2-hydroxypropyltrimethylammonium chloride was obtained by evaporating the reaction mixture to dryness.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04814506 |
|---|
| 出典データセット | uspto-grants-1989_03 |
|---|
| ORD ID | ord-238c38f59d2e443fb190bf3a294c551d |
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| 出典メモ | uspto-grants-1989_03 |
|---|
