5-Bromo-1,1-dimethoxypentane → 2-(5,5-Dimethoxypentyl)-1H-isoindole-1,3(2H)-dione
反応式
[C:1]1(=[O:11])[NH:5][C:4](=[O:6])[C:3]2=[CH:7][CH:8]=[CH:9][CH:10]=[C:2]12.[K].[CH3:13][O:14][CH:15]([O:21][CH3:22])[CH2:16][CH2:17][CH2:18][CH2:19]Br>CN(C)C=O>[CH3:13][O:14][CH:15]([O:21][CH3:22])[CH2:16][CH2:17][CH2:18][CH2:19][N:5]1[C:1](=[O:11])[C:2]2[C:3](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:4]1=[O:6]参加物
4
実験手順
A mixture of potassium phthalimide (0.48 g) and 5-bromopentanal dimethyl acetal (0.50 g) in dry dimethylformamide (3 ml) was stirred at 90° for 5 h and then allowed to cool. The resultant yellow suspension was then partitioned between water (30 ml) and ethyl acetate (3×30 ml). The combined organic extracts were then dried (Na2SO4) and concentrated in vauco.
後処理
- temperatureto cool
- customThe resultant yellow suspension was then partitioned between water (30 ml) and ethyl acetate (3×30 ml)
- dry with materialThe combined organic extracts were then dried (Na2SO4)
- concentrationconcentrated in vauco
出典と根拠
- ORDレコード
- ord-7b14b9fab9fc426eb1278cc5b0f1bd6e
- 出典データセット
- uspto-grants-1989_03
- 特許番号
- US04816470
反応ノート
読み込み中…