Bromocyclopentane → ethyl (2Z)-2-cyclopentyloxyimino-3-oxobutanoate

HRID 1194881

反応式

HRID 1194881 の反応式
[OH:1]/[N:2]=[C:3](/[C:9](=[O:11])[CH3:10])\[C:4]([O:6][CH2:7][CH3:8])=[O:5].[CH:12]1(Br)[CH2:16][CH2:15][CH2:14][CH2:13]1>>[CH:12]1([O:1]/[N:2]=[C:3](/[C:9](=[O:11])[CH3:10])\[C:4]([O:6][CH2:7][CH3:8])=[O:5])[CH2:16][CH2:15][CH2:14][CH2:13]1

参加物

3

反応物 2

HCID 8728BromocyclopentaneHCID 178472876HCID 178472876、化合物

生成物 1

HCID 14864952ethyl (2Z)-2-cyclopentyloxyimino-3-oxobutanoate収率 80%

実験手順

Ethyl (Z)-2-(hydroxyimino)-3-oxobutyrate (7.9 g) was treated with cyclopentyl bromide as described in Example 4a, Method 2, except that the reaction was stirred overnight to give the title compound as a colourless liquid (9.Og, 80%), (Found: M+ +H, 228.1241. C11H17NO4 requires M+H, 228.1236); νmax (film) 2960 1745, 1700 cm-1 ; δH (CDCl3) 1.30 (3H, t), 1.6-2.0 (8H, m), 2.37 (3H, s), 4.31 (2H, q),and 4.87 (1H, m).

出典と根拠

ORDレコード
ord-6b9cb141c450485b99498dc72045c12b
出典データセット
uspto-grants-1989_03
特許番号
US04816452

関連ノート

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