Dimethyl Sulfoxide → HCID 86745743、化合物

HRID 1195243ノート

反応式

HRID 1195243 の反応式
Cl.[CH:2]1([C:5]([C:7]2([CH3:10])[CH2:9][CH2:8]2)=[NH:6])[CH2:4]C1.[Cl:11]([O-:15])(=[O:14])(=[O:13])=[O:12].[NH4+].[CH3:17]S(C)=O>>[Cl:11]([O-:15])(=[O:14])(=[O:13])=[O:12].[NH3+:6][CH:5]1[C:7]2[CH2:9][CH2:8][CH2:17][C:10]=2[CH2:4][CH2:2]1

参加物

4

反応物 3

HCID 679Dimethyl SulfoxideHCID 24639Ammonium perchlorateHCID 19819014HCID 19819014、化合物

生成物 1

HCID 86745743HCID 86745743、化合物収率 43%

反応条件

温度
100 °C

実験手順

To a solution of 1-cyclopropyl-1-(1-methylcyclopropyl)methanimine hydrochloride (0.060 g, 0.38 mmol) in 0.60 ml of dimethyl sulfoxide was added 0.088 g (0.75 mmol) of ammonium perchlorate. The mixture was heated with stirring at 100° C. for 20 hours. The solvent was distilled out in vacuo and ether was added to the residue. Precipitated crystals was obtained and recrystallized from ethanol to afford 0.36 g (Yield: 43%) of the desired compound.

後処理

  1. temperatureThe mixture was heated
  2. distillationThe solvent was distilled out in vacuo and ether
  3. additionwas added to the residue
  4. customPrecipitated crystals
  5. customwas obtained
  6. customrecrystallized from ethanol

出典と根拠

ORDレコード
ord-faae784c562345d58e00a7c07ea2c7c1
出典データセット
uspto-grants-1992_05
特許番号
US05110945

反応ノート

読み込み中…