Methanol → Benzoic acid, 2-((3-(trifluoromethyl)phenyl)amino)-, methyl ester

HRID 1195872

反応式

HRID 1195872 の反応式
[F:1][C:2]([F:20])([F:19])[C:3]1[CH:4]=[C:5]([NH:9][C:10]2[CH:18]=[CH:17][CH:16]=[CH:15][C:11]=2[C:12]([OH:14])=[O:13])[CH:6]=[CH:7][CH:8]=1.S(=O)(=O)(O)O.[CH3:26]O>>[F:1][C:2]([F:19])([F:20])[C:3]1[CH:4]=[C:5]([NH:9][C:10]2[CH:18]=[CH:17][CH:16]=[CH:15][C:11]=2[C:12]([O:14][CH3:26])=[O:13])[CH:6]=[CH:7][CH:8]=1

参加物

4

反応物 3

HCID 887MethanolHCID 1118Sulfuric AcidHCID 3371Flufenamic Acid

生成物 1

HCID 200813Benzoic acid, 2-((3-(trifluoromethyl)phenyl)amino)-, methyl ester収率 71%

実験手順

Reaction of 2-[[3-(trifluoromethyl)phenyl]amino] benzoic acid with methanol and sulfuric acid according to the procedure of Example 26 gives a 71% yield of 2-[[3-(trifluoromethyl)phenyl]amino]benzoic acid, methyl ester as a colorless oil.

出典と根拠

ORDレコード
ord-7004dd01d3034ea8a81d4fcefd8b1833
出典データセット
uspto-grants-1992_05
特許番号
US05112846

関連ノート

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