Hydrochloric Acid → 4-(3,4-Dihydroxy-5-nitrophenyl)-3-methylbut-3-en-2-one

HRID 1195931ノート

反応式

HRID 1195931 の反応式
[OH:1][C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([N+:11]([O-:13])=[O:12])[C:9]=1[OH:10])[CH:5]=O.Cl.CCOCC.[CH3:20][C:21](=[O:24])[CH2:22][CH3:23]>>[OH:1][C:2]1[CH:3]=[C:4]([CH:5]=[C:22]([CH3:23])[C:21](=[O:24])[CH3:20])[CH:7]=[C:8]([N+:11]([O-:13])=[O:12])[C:9]=1[OH:10]

参加物

5

反応物 4

HCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 6569Methyl Ethyl KetoneHCID 57489573,4-Dihydroxy-5-nitrobenzaldehyde

生成物 1

HCID 540099494-(3,4-Dihydroxy-5-nitrophenyl)-3-methylbut-3-en-2-one

実験手順

A solution containing 0.5 g of 3,4-dihydroxy-5-nitrobenzaldehyde in 2.0 ml of butanone was saturated with gaseous hydrogen chloride. After standing over night ether was added to the solution and it was filtered. The product was crystallized from isopropanol, yield 0.2 g (30%), m.p. 139°-141° C.

後処理

  1. waitAfter standing over night
  2. filtrationwas filtered
  3. customThe product was crystallized from isopropanol, yield 0.2 g (30%), m.p. 139°-141° C.

出典と根拠

ORDレコード
ord-f1b1fa0801bf483a8fe548f1efdb8fcf
出典データセット
uspto-grants-1992_05
特許番号
US05112861

反応ノート

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